Steps Towards the Formation of A Protocell: The Possible Role of Short Peptides
Identifieur interne : 002C26 ( Main/Exploration ); précédent : 002C25; suivant : 002C27Steps Towards the Formation of A Protocell: The Possible Role of Short Peptides
Auteurs : Maya Fishkis [Canada, Niger]Source :
- Origins of Life and Evolution of Biospheres [ 0169-6149 ] ; 2007-12-01.
English descriptors
Abstract
Abstract: The paper deals with molecular self-organization leading to formation of a protocell. Plausible steps towards a protocell include: polymerization of peptides and oligonucleotides on mineral surfaces; coevolution of peptides and oligonucleotides with formation of collectively autocatalytic sets; self-organization of short peptides into vesicles; entrapment of the peptide/oligonucleotide systems in mixed peptide and simple amphiphile membranes; and formation of functioning protocells with metabolism and cell division. The established propensity of short peptides to self-ordering and to formation of vesicles makes this sequence plausible. We further suggest that evolution of a protocell produced cellular ancestors of viruses as well as ancestors of cellular organisms.
Url:
DOI: 10.1007/s11084-007-9111-4
Affiliations:
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